# VRTX · Vertex Pharmaceuticals Inc / MA Snapshot 2026-10-26 · CIK 0000875320 · Nasdaq · Pharmaceutical Preparations Price 523.93 (2026-10-23, Alpaca Market Data (consolidated SIP daily bar)) · Market cap 132.8 B Machine-readable: https://theclaudetrader.com/s/VRTX.json · index: https://theclaudetrader.com/llms.txt ## Scores ### Graham Defensive: 47.0 (ok) · complete: True · missing tests: none · current inputs as of 2025-12-31 · stale inputs: Revenue · history 2014–2025 · price 2026-10-23 · verification {'verified': 0, 'mismatch': 0, 'unverified': 23, 'not_cross_checked': 2} · computed 2026-10-26 · rules https://theclaudetrader.com/p/graham - 1 Adequate size: 12.0 revenue $B · threshold >= 1 · points 5.0/5 - 2a Current ratio: 3.19 · threshold >= 2.0 · points 15.0/15 - 2b Long-term debt vs working capital: 0.38 LTD / WC · threshold <= 1.0 · points 15.0/15 - 3 Positive earnings each of 10 years: 8 of 10 · threshold 10 of 10 · points 12.0/15 - 4 Dividends every year for 20 years: 0 of 20 · threshold 20 of 20 · points 0.0/15 - 5 EPS growth, 3-yr avg now vs 10 yrs ago: -1.97 -> 9.04 · threshold >= +33% · points 0.0/10 - 6 P/E on 3-year average EPS: 57.9 · threshold <= 15 · points 0.0/15 - 7 P/B <= 1.5, or P/E x P/B <= 22.5: P/B 6.56, product 380.0 · threshold <= 1.5 or <= 22.5 · points 0.0/10 Inputs: - Price (close, per traded unit): 523.93 · 2026-10-23 · Alpaca Market Data (consolidated SIP daily bar) · https://docs.alpaca.markets/docs/historical-stock-data-1 - Revenue: 12001300000.0 · 2025-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - liabilities: 7175400000.0 · 2026-06-30 · SEC XBRL Liabilities · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_liabilities: 3937900000.0 · 2026-06-30 · SEC XBRL LiabilitiesCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_assets: 12543700000.0 · 2026-06-30 · SEC XBRL AssetsCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_liabilities: 3937900000.0 · 2026-06-30 · SEC XBRL LiabilitiesCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - equity: 20247900000.0 · 2026-06-30 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - Net income FY2016: -112052000.0 · 2016-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532019000006/ · unverified - Net income FY2017: 263484000.0 · 2017-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532020000007/ · unverified - Net income FY2018: 2096896000.0 · 2018-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/ · unverified - Net income FY2019: 1176800000.0 · 2019-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ · unverified - Net income FY2020: 2711700000.0 · 2020-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified - Net income FY2021: 2342100000.0 · 2021-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Net income FY2022: 3322000000.0 · 2022-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Net income FY2023: 3619600000.0 · 2023-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2024: -535600000.0 · 2024-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2025: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Dividend years (Yahoo): [] · · Yahoo Finance dividend history · https://finance.yahoo.com/quote/VRTX/history?filter=div · unverified - EPS diluted FY2014: -3.14 · 2014-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532017000017/ · unverified - EPS diluted FY2015: -2.31 · 2015-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/ · unverified - EPS diluted FY2016: -0.46 · 2016-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532019000006/ · unverified - EPS diluted FY2023: 13.89 · 2023-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - EPS diluted FY2024: -2.08 · 2024-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - EPS diluted FY2025: 15.32 · 2025-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Shares outstanding: 253460924.0 · 2026-07-31 · SEC cover page 10-Q 0000875320-26-000259 (253,460,924 shares (single class on cover)); filing document https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/vrtx-20260630.htm · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/R1.htm ### Magic Formula: — (insufficient data (no fresh property, plant and equipment (PropertyPlantAndEquipmentNet) reported)) · complete: None · missing tests: none · current inputs as of None · stale inputs: none · history None–None · price None · verification None · computed 2026-10-26 · rules https://theclaudetrader.com/p/magic_formula ### Momentum: 72.1 (ok) · complete: True · missing tests: none · current inputs as of 2026-10-23 · stale inputs: none · history None–None · price 2026-10-23 · verification None · computed 2026-10-26 · rules https://theclaudetrader.com/p/momentum - 12-1 month return: 22.2 % · threshold · points 34.8/50 - 6 month return: 20.4 % · threshold · points 15.8/20 - Price / 52-week high: 0.939 · threshold · points 14.1/15 - Volatility penalty (60d annualised): 28.2 % · threshold · points 7.4/15 Inputs: - Adjusted close series (14 months): 523.93 · 2026-10-23 · Yahoo Finance / Alpaca Market Data daily history · ### Insider: 0.0 (no open-market transactions in window) · complete: True · missing tests: none · current inputs as of 2026-10-23 · stale inputs: none · history None–None · price None · verification None · computed 2026-10-26 · rules https://theclaudetrader.com/p/insider - Open-market buy value / market cap (percentile among buyers): 0.0 bp · threshold · points 0.0/35 - Distinct buyers: 0 · threshold · points 0.0/25 - Buyer seniority: 0.0 · threshold · points 0.0/20 - Recency (half-life 30d): 0.0 · threshold · points 0.0/10 - Sales penalty (excludes 10b5-1 plan sales): 0.0 bp · threshold · points -0.0/0 ### Buffett Quality: 66.0 (partial: 4) · complete: False · missing tests: 4 · current inputs as of 2026-07-31 · stale inputs: none · history 2016–2025 · price 2026-10-23 · verification {'verified': 0, 'mismatch': 0, 'unverified': 46, 'not_cross_checked': 2} · computed 2026-10-26 · rules https://theclaudetrader.com/p/buffett - 1 Average return on equity (net income / year-end equity): 22.9% over 8 yrs · threshold >= 15% · points 25.0/25 - 2 Profitable every year: 8 of 10 · threshold all years · points 12.0/15 - 3 Net income growth, 3-yr average now vs start of window: +17.7% a year · threshold >= +10% · points 10.0/10 - 4 Borrowings / 3-yr average earnings (years to repay): None · threshold <= 4 · points None/15 - 5 Operating margin, 5-yr average: 31.3% · threshold >= 20% · points 10.0/10 - 6 Free cash flow / net income, 5-yr (operating cash flow minus capex): 0.95 · threshold >= 1.0 · points 9.0/10 - 7 Owner-earnings yield (3-yr avg free cash flow / market cap): 1.4% · threshold >= 7% · points 0.0/15 Inputs: - Price (close, per traded unit): 523.93 · 2026-10-23 · Alpaca Market Data (consolidated SIP daily bar) · https://docs.alpaca.markets/docs/historical-stock-data-1 - Net income FY2018: 2096896000.0 · 2018-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/ · unverified - Equity at FY2018 end: 4435200000.0 · 2018-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ · unverified - Net income FY2019: 1176800000.0 · 2019-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ · unverified - Equity at FY2019 end: 6085200000.0 · 2019-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified - Net income FY2020: 2711700000.0 · 2020-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified - Equity at FY2020 end: 8686800000.0 · 2020-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Net income FY2021: 2342100000.0 · 2021-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Equity at FY2021 end: 10100000000.0 · 2021-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Net income FY2022: 3322000000.0 · 2022-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Equity at FY2022 end: 13912700000.0 · 2022-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2023: 3619600000.0 · 2023-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Equity at FY2023 end: 17580400000.0 · 2023-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2024: -535600000.0 · 2024-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Equity at FY2024 end: 16409600000.0 · 2024-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - Net income FY2025: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Equity at FY2025 end: 18665800000.0 · 2025-12-31 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - Net income FY2016: -112052000.0 · 2016-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532019000006/ · unverified - Net income FY2017: 263484000.0 · 2017-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532020000007/ · unverified - Net income FY2018: 2096896000.0 · 2018-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/ · unverified - Net income FY2019: 1176800000.0 · 2019-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ · unverified - Net income FY2020: 2711700000.0 · 2020-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified - Net income FY2021: 2342100000.0 · 2021-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Net income FY2022: 3322000000.0 · 2022-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Net income FY2023: 3619600000.0 · 2023-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2024: -535600000.0 · 2024-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2025: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Operating income FY2021: 2782100000.0 · 2021-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Revenue FY2021: 7574400000.0 · 2021-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Operating income FY2022: 4307400000.0 · 2022-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Revenue FY2022: 8930700000.0 · 2022-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Operating income FY2023: 3832000000.0 · 2023-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Revenue FY2023: 9869200000.0 · 2023-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Operating income FY2024: -232900000.0 · 2024-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Revenue FY2024: 11020100000.0 · 2024-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Operating income FY2025: 4173300000.0 · 2025-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Revenue FY2025: 12001300000.0 · 2025-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Operating cash flow FY2021: 2643500000.0 · 2021-12-31 · SEC XBRL NetCashProvidedByUsedInOperatingActivities · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Capital expenditure FY2021: 235000000.0 · 2021-12-31 · SEC XBRL PaymentsToAcquirePropertyPlantAndEquipment · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Operating cash flow FY2022: 4129900000.0 · 2022-12-31 · SEC XBRL NetCashProvidedByUsedInOperatingActivities · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified ### Lynch GARP: 26.7 (partial: 4, 6) · complete: False · missing tests: 4, 6 · current inputs as of None · stale inputs: none · history 2020–2025 · price 2026-10-23 · verification {'verified': 0, 'mismatch': 0, 'unverified': 2, 'not_cross_checked': 1} · computed 2026-10-26 · rules https://theclaudetrader.com/p/lynch - 1 PEG: P/E divided by 5-yr EPS growth (in % points): 4.13 · threshold <= 1.0 · points 0.0/30 - 2 EPS growth, 5-yr compound rate: +8.3% a year · threshold 12% to 35% a year · points 13.8/20 - 3 P/E on latest annual EPS: 34.2 · threshold <= 25 · points 3.9/10 - 4 Borrowings / equity: None · threshold <= 0.5 · points None/15 - 5 Years of the last 5 in which EPS rose: 3 of 5 · threshold 5 of 5 · points 9.0/15 - 6 Net cash (cash minus borrowings) / market cap: None · threshold >= +10% · points None/10 Inputs: - Price (close, per traded unit): 523.93 · 2026-10-23 · Alpaca Market Data (consolidated SIP daily bar) · https://docs.alpaca.markets/docs/historical-stock-data-1 - EPS diluted FY2025: 15.32 · 2025-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - EPS diluted FY2020: 10.29 · 2020-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified ### Graham Enterprising: 37.0 (partial: 2) · complete: False · missing tests: 2 · current inputs as of 2026-06-30 · stale inputs: none · history 2020–2025 · price 2026-10-23 · verification {'verified': 0, 'mismatch': 0, 'unverified': 11, 'not_cross_checked': 3} · computed 2026-10-26 · rules https://theclaudetrader.com/p/graham_enterprising - 1 Current ratio: 3.19 · threshold >= 1.5 · points 15.0/15 - 2 Borrowings vs working capital: None · threshold <= 1.1x · points None/15 - 3 No earnings deficit in the last 5 years: 4 of 5 profitable · threshold 5 of 5 · points 12.0/15 - 4 Pays a current dividend: no · threshold yes · points 0.0/10 - 5 EPS higher than five years earlier: 10.29 -> 15.32 · threshold higher · points 10.0/10 - 6 Price / book value per share: 6.56 · threshold <= 1.2 · points 0.0/20 - 7 Price / net current asset value per share (current assets minus all liabilities): 24.74 · threshold <= 0.67 · points 0.0/15 Inputs: - Price (close, per traded unit): 523.93 · 2026-10-23 · Alpaca Market Data (consolidated SIP daily bar) · https://docs.alpaca.markets/docs/historical-stock-data-1 - current_assets: 12543700000.0 · 2026-06-30 · SEC XBRL AssetsCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_liabilities: 3937900000.0 · 2026-06-30 · SEC XBRL LiabilitiesCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - Net income FY2021: 2342100000.0 · 2021-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ · unverified - Net income FY2022: 3322000000.0 · 2022-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ · unverified - Net income FY2023: 3619600000.0 · 2023-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2024: -535600000.0 · 2024-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Net income FY2025: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - Dividend years (Yahoo): [] · · Yahoo Finance dividend history · https://finance.yahoo.com/quote/VRTX/history?filter=div - EPS diluted FY2025: 15.32 · 2025-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - EPS diluted FY2020: 10.29 · 2020-12-31 · SEC XBRL EarningsPerShareDiluted · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ · unverified - equity: 20247900000.0 · 2026-06-30 · SEC XBRL StockholdersEquity · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - Shares outstanding: 253460924.0 · 2026-07-31 · SEC cover page 10-Q 0000875320-26-000259 (253,460,924 shares (single class on cover)); filing document https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/vrtx-20260630.htm · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/R1.htm - liabilities: 7175400000.0 · 2026-06-30 · SEC XBRL Liabilities · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified ### Piotroski F-Score: 66.7 (partial: 5) · complete: False · missing tests: 5 · current inputs as of None · stale inputs: none · history 2024–2026 · price None · verification {'verified': 0, 'mismatch': 0, 'unverified': 23, 'not_cross_checked': 0} · computed 2026-10-26 · rules https://theclaudetrader.com/p/piotroski - 1 Return on assets is positive: 15.4% · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 2 Operating cash flow is positive: 3,631M · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 3 Return on assets improved on the prior year: -2.4% -> 15.4% · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 4 Operating cash flow exceeds net income (accruals): 3,631M vs 3,953M · threshold pass = 1 · points 0.0/11.11111111111111 - 5 Long-term debt / assets fell: None · threshold pass = 1 · points None/11.11111111111111 - 6 Current ratio improved: 2.69 -> 2.90 · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 7 No new shares issued (share count did not rise): 256M -> 253M · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 8 Operating margin improved (stand-in for gross margin, which the dataset does not carry): -2.1% -> 34.8% · threshold pass = 1 · points 11.11111111111111/11.11111111111111 - 9 Asset turnover (revenue / assets) improved: 0.49 -> 0.47 · threshold pass = 1 · points 0.0/11.11111111111111 Inputs: - net_income 2025-12-31: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - total_assets 2025-12-31: 25643000000.0 · 2025-12-31 · SEC XBRL Assets · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - cfo 2025-12-31: 3631400000.0 · 2025-12-31 · SEC XBRL NetCashProvidedByUsedInOperatingActivities · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - net_income 2025-12-31: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - net_income 2024-12-31: -535600000.0 · 2024-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - total_assets 2025-12-31: 25643000000.0 · 2025-12-31 · SEC XBRL Assets · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - total_assets 2024-12-31: 22533200000.0 · 2024-12-31 · SEC XBRL Assets · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - cfo 2025-12-31: 3631400000.0 · 2025-12-31 · SEC XBRL NetCashProvidedByUsedInOperatingActivities · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - net_income 2025-12-31: 3953200000.0 · 2025-12-31 · SEC XBRL NetIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - current_assets 2025-12-31: 11201000000.0 · 2025-12-31 · SEC XBRL AssetsCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_assets 2024-12-31: 9596400000.0 · 2024-12-31 · SEC XBRL AssetsCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - current_liabilities 2025-12-31: 3861200000.0 · 2025-12-31 · SEC XBRL LiabilitiesCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - current_liabilities 2024-12-31: 3564600000.0 · 2024-12-31 · SEC XBRL LiabilitiesCurrent · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - shares_out 2026-07-31: 253460924.0 · 2026-07-31 · SEC XBRL EntityCommonStockSharesOutstanding · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - shares_out 2025-07-31: 256390651.0 · 2025-07-31 · SEC XBRL EntityCommonStockSharesOutstanding · https://www.sec.gov/Archives/edgar/data/875320/000087532025000216/ · unverified - operating_income 2025-12-31: 4173300000.0 · 2025-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - operating_income 2024-12-31: -232900000.0 · 2024-12-31 · SEC XBRL OperatingIncomeLoss · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - revenue 2025-12-31: 12001300000.0 · 2025-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - revenue 2024-12-31: 11020100000.0 · 2024-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - revenue 2025-12-31: 12001300000.0 · 2025-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - revenue 2024-12-31: 11020100000.0 · 2024-12-31 · SEC XBRL RevenueFromContractWithCustomerExcludingAssessedTax · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified - total_assets 2025-12-31: 25643000000.0 · 2025-12-31 · SEC XBRL Assets · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/ · unverified - total_assets 2024-12-31: 22533200000.0 · 2024-12-31 · SEC XBRL Assets · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ · unverified ## Market value, source trail - Formula: market_value = traded_price (price date) / depositary_ratio x latest point-in-time SEC shares outstanding (share-count date shown; from the filing cover page, summed across share classes only where the issuer filing verifies the classes are economically equivalent (rule + evidence URL in the source text), else withheld; priced at the primary listed class, so where other classes trade at a different price the value is an approximation; restated only for issuer-verified splits after the count date); weighted-average share counts are never used - Traded price: 523.93 on 2026-10-23 (USD per traded unit (share or ADS)) · https://docs.alpaca.markets/docs/historical-stock-data-1 - SEC shares outstanding: 253,460,924 underlying shares, period 2026-07-31, SEC cover page 10-Q 0000875320-26-000259 (253,460,924 shares (single class on cover)); filing document https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/vrtx-20260630.htm, accession 0000875320-26-000259 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000259/R1.htm - Depositary ratio: 1.0 (domestic; 10-K filer; SEC shares are the traded units) · None - Market value (price date x latest reported shares): 132,795,781,911 USD; 523.93 (price 2026-10-23) / 1 x 253,460,924 (shares at 2026-07-31) = 132,795,781,911 ## Revenue by fiscal year (SEC XBRL; FY = calendar year in which the fiscal year ends) - FY2013 (ended 2013-12-31): 1211975000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532016000067/ - FY2014 (ended 2014-12-31): 580415000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532017000017/ - FY2015 (ended 2015-12-31): 1032336000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/ - FY2016 (ended 2016-12-31): 1702177000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/ - FY2017 (ended 2017-12-31): 2488652000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/ - FY2018 (ended 2018-12-31): 3047597000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/ - FY2019 (ended 2019-12-31): 4162800000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ - FY2020 (ended 2020-12-31): 6205700000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ - FY2021 (ended 2021-12-31): 7574400000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ - FY2022 (ended 2022-12-31): 8930700000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ - FY2023 (ended 2023-12-31): 9869200000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ - FY2024 (ended 2024-12-31): 11020100000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ - FY2025 (ended 2025-12-31): 12001300000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ ## Net income by fiscal year (SEC XBRL) - FY2013 (ended 2013-12-31): -445028000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532016000067/ - FY2014 (ended 2014-12-31): -738555000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532017000017/ - FY2015 (ended 2015-12-31): -556334000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532018000009/ - FY2016 (ended 2016-12-31): -112052000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532019000006/ - FY2017 (ended 2017-12-31): 263484000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532020000007/ - FY2018 (ended 2018-12-31): 2096896000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532021000006/ - FY2019 (ended 2019-12-31): 1176800000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532022000007/ - FY2020 (ended 2020-12-31): 2711700000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532023000007/ - FY2021 (ended 2021-12-31): 2342100000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532024000062/ - FY2022 (ended 2022-12-31): 3322000000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532025000053/ - FY2023 (ended 2023-12-31): 3619600000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ - FY2024 (ended 2024-12-31): -535600000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ - FY2025 (ended 2025-12-31): 3953200000.0 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000056/ ## EPS diluted by fiscal year (split-adjusted to today's share basis; as filed in brackets) - FY2013 (ended 2013-12-31): -1.98 [filed -1.98, split factor 1.0] - FY2014 (ended 2014-12-31): -3.14 [filed -3.14, split factor 1.0] - FY2015 (ended 2015-12-31): -2.31 [filed -2.31, split factor 1.0] - FY2016 (ended 2016-12-31): -0.46 [filed -0.46, split factor 1.0] - FY2017 (ended 2017-12-31): 1.04 [filed 1.04, split factor 1.0] - FY2018 (ended 2018-12-31): 8.09 [filed 8.09, split factor 1.0] - FY2019 (ended 2019-12-31): 4.51 [filed 4.51, split factor 1.0] - FY2020 (ended 2020-12-31): 10.29 [filed 10.29, split factor 1.0] - FY2021 (ended 2021-12-31): 9.01 [filed 9.01, split factor 1.0] - FY2022 (ended 2022-12-31): 12.82 [filed 12.82, split factor 1.0] - FY2023 (ended 2023-12-31): 13.89 [filed 13.89, split factor 1.0] - FY2024 (ended 2024-12-31): -2.08 [filed -2.08, split factor 1.0] - FY2025 (ended 2025-12-31): 15.32 [filed 15.32, split factor 1.0] ## Dividend years (Yahoo history) none ## Insider transactions (SEC Form 4 data set, latest 40) - 2026-07-02 S McKechnie Duncan (officer) 1541 @ 519.00 = 799779 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000243/ - 2026-07-02 S Tatsis Ourania (officer) 1500 @ 524.99 = 787485 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000245/ - 2026-07-01 S Liu Joy (officer) 828 @ 502.71 = 416244 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000241/ - 2026-06-26 S Bozic Carmen (officer) 596 @ 482.50 = 287570 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000239/ - 2026-06-18 S Bozic Carmen (officer) 1020 @ 462.17 = 471413 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000237/ - 2026-06-15 S Bozic Carmen (officer) 4062 @ 450.00 = 1827900 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000235/ - 2026-06-05 S Bozic Carmen (officer) 1745 @ 450.00 = 785250 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000233/ - 2026-06-01 S Liu Joy (officer) 828 @ 439.91 = 364245 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000230/ - 2026-05-29 S Bozic Carmen (officer) 1974 @ 450.00 = 888300 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000228/ - 2026-05-15 S Bozic Carmen (officer) 1354 @ 453.45 = 613971 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000225/ - 2026-05-15 S Bunnage Mark E. (officer) 33 @ 453.45 = 14964 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000226/ - 2026-05-12 S Bozic Carmen (officer) 6988 @ 450.00 = 3144600 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000222/ - 2026-05-04 S Bhatia Sangeeta N. (director) 318 @ 423.73 = 134746 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000175/ - 2026-05-01 S Liu Joy (officer) 1104 @ 425.02 = 469222 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000183/ - 2026-04-01 S Liu Joy (officer) 978 @ 449.17 = 439288 · https://www.sec.gov/Archives/edgar/data/875320/000087532026000157/ ## Links - sec_filings: https://www.sec.gov/edgar/browse/?CIK=0000875320 - sec_xbrl_companyfacts: https://data.sec.gov/api/xbrl/companyfacts/CIK0000875320.json - sec_form4: https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0000875320&type=4 - sec_8k: https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0000875320&type=8-K - yahoo: https://finance.yahoo.com/quote/VRTX - stooq: https://stooq.com/q/d/?s=vrtx.us - morningstar (link only, nothing stored): https://www.morningstar.com/search?query=VRTX - finviz (link only, nothing stored): https://finviz.com/quote.ashx?t=VRTX - stockanalysis (link only, nothing stored): https://stockanalysis.com/stocks/vrtx/ - seeking_alpha (link only, nothing stored): https://seekingalpha.com/symbol/VRTX - openinsider (link only, nothing stored): http://openinsider.com/search?q=VRTX - google_news (link only, nothing stored): https://news.google.com/rss/search?q=VRTX+stock Cite as: The Claude Trader snapshot 2026-10-26, https://theclaudetrader.com/s/VRTX; data from SEC EDGAR XBRL and market prices (Alpaca Market Data, Yahoo Finance) to 2026-10-23. Scores are deterministic rule outputs from public filings. fair_value_model is a labelled model estimate from the same filings (method at /fair-value), not an opinion or recommendation.